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  • Ensuring reliability in large clinical trials for dementia

    When investigating the brain, scientists work with datasets containing vast amounts of detail. This includes the brain scans that they’ll be working with. Variations between images could indicate a particular character of the Alzheimer’s disease development. They could indicate the role of a particular chemical in the brain, or the role of a particular area in the brain.

  • Tau-PET imaging

    Researchers will carry out additional PET scanning of 100 people who have already had PET scans as part of their involvement in two existing health study cohorts – EPAD and PREVENT. The extra information they collect on the 'tau' protein, when combined with existing data from these participants, will create a very rich dataset for modelling the early stages of Alzheimer's disease and subsequent dementia.

  • Deep and Frequent Phenotyping study

    One of the big challenges facing dementia researchers is how to diagnose and track Alzheimer’s disease in its earliest stages – often decades before symptoms start to show. The Deep and Frequent Phenotyping study will help scientists to identify the best early warning signs of this condition, and to track responses to treatments.

  • New brain scan may pinpoint early progression of Alzheimer’s disease

    The New Therapeutics in Alzheimer's Disease (NTAD) study, supported by Dementias Platform UK (DPUK), is testing new brain scans that are revealing early changes in the brain that are a signature of Alzheimer’s disease.

  • Study into early Alzheimer's disease treatments

    The New Therapeutics into Alzheimer's Disease (NTAD) study is looking to detect markers of the disease before symptoms show. These markers for the disease will be used to test whether experimental treatments can delay, or even prevent, the progression of the disease.