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Our Clinical Studies Register comprises more than 58,000 research participants who have already undergone extensive characterisation and have pre-existing consent for re-contact through their parent DPUK cohort.

Our Clinical Studies Register comprises more than 58,000 research participants who have already undergone extensive characterisation and have pre-existing consent for re-contact through their parent DPUK cohort.

By combining detailed phenotyping and, where available, genomic data from cohorts, the Clinical Studies Register enables risk stratification per hypothesis at a level of detail and convenience that would not otherwise be available.

Clinical register and sites

The clinical arm of the Trials Delivery Framework contains 30 UK sites for clinical trial recruitment and delivery, at NHS and academic research sites, incorporating all the UK brain health clinics across the UK and beyond. By developing such an extensive network in both research active academic sites and less research focused NHS Trusts with a broad geographic spread, we aim to provide more representative, real world data and populations to trials. We are now also recruiting primary care practices to our network to provide even further reach for trial recruitment. Data from these clinical sites is being centrally managed within the DPUK Data Portal, allowing us to create a large and very scalable data set of blood, clinical imaging and cognitive data across multiple UK clinical sites for efficient and effective recruitment to clinical trials.