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Here you'll find all the latest news from DPUK.

Testing for hearing loss could 'reduce Dementia risk' later in life


Research by Dr. Sarah Bauermeister of Dementias Platform UK at the Department of Psychiatry, University of Oxford, into hearing loss and its impacts on the progress of dementia in later life has featured in extensive media coverage of a Brain Health Check-In tool created by Alzheimer's Research UK.

DPUK welcomes government’s £50m investment in MND research

The pledge of £3 million investment by the Medical Research Council towards a translational accelerator will enable the MND community to work in partnership with Dementias Platform UK and the UK Dementia Research Institute.

DPUK-funded study shows symptoms for Alzheimer’s can be predicted in preclinical models

Oxford University researchers have recently established that laboratory models of Alzheimer’s can reflect in-life clinical symptoms. The team found that nerve cells created in the laboratory from Alzheimer’s disease stem cells reacted to amyloid proteins in a similar way in which the brains of the same Alzheimer’s disease patients reacted to high amyloid protein burden load.

Comment: Professor Bart De Strooper steps down as Director of the UK Dementia Research Institute

After six years in his role, Prof De Strooper will now return full time to focus on his research on Alzheimer’s disease. DPUK is delighted that he and his lab will continue to work towards translational neuroscience and dementia research.

New report signposts global dementia data assets for benefit of researchers

Dementias Platform UK (DPUK) today launches its new ‘Data Landscape Report’ – the most comprehensive overview to date of available dementia data assets worldwide.

Cumulative life adversity impacts cognition in later adulthood

New research reveals the association between cumulative life course adversity, depression, and cognitive performance. The findings are published in the scientific journal Nature Scientific Reports.

Digital healthcare company Five Lives joins DPUK consortium as industry partner

DPUK is delighted to welcome the health technology company Five Lives as its newest industry partner.

Reaction: UK government confirms major new funding for dementia research

The UK government has announced the launch of a ‘national mission’ to tackle dementia, pledging again to double research funding to £160m per year by 2024.

Diadem partners with DPUK to advance diagnosis and treatment of Alzheimer’s disease

Diadem SpA, a company developing AlzoSure Predict, the first blood-based test for the early prediction of progression to Alzheimer’s disease, has joined DPUK as an industry partner.

Researchers use DPUK Data Portal to explore pathways linking social and lifestyle factors with cognitive function

A new study in the DPUK Data Portal has found that social and lifestyle factors – such as education, income and physical activity – have a direct effect on cognitive performance. The researchers also showed that late-life lifestyle factors may help preserve cognitive function indirectly by reducing the degeneration of brain cells.

Study finds childhood deprivation is linked to faster cognitive decline

Our circumstances and experiences in childhood can have lasting consequences for our thinking skills, according to a new study funded by Dementias Platform UK.

DPUK Data Portal passes 1,000 cohort access requests

Researchers have made more than 1,000 applications to access cohorts within the DPUK Data Portal.

Genetic and activity information will enhance detail within Great Minds volunteer registry

DPUK’s Great Minds register gives researchers access to more than 6,800 well-characterised volunteers who are ready and willing to take part in dementia studies.

Study in DPUK Data Portal finds recurrent depression affects cognition in over-50s

A large-scale analysis of two UK datasets has shown that recurrent depression affects performance in several tests of thinking skills. However, this difference was not altered by taking anti-inflammatory medications such as Ibuprofen, suggesting that neuroinflammation may not be the underlying process driving depression’s effect on cognition.

New study begins measuring brain scans to score brain health

Researcher Dr Jodi Watt is to examine thousands of magnetic resonance imaging (MRI) brain scans to identify patterns of brain health. Based at the Glasgow Royal Infirmary, Dr Watt will be using the UK Biobank Cohort and the European Prevention of Alzheimer’s Dementia (EPAD) cohort for her exciting postdoctoral project.

DPUK Director signs open letter calling for dementia 'medicines taskforce'

DPUK Director Professor John Gallacher has co-signed an open letter to the UK prime minister, published by the Sunday Times, calling for greater investment in dementia research, taking inspiration from the COVID-19 vaccines effort.

Cognitive frailty confirmed as a feature of normal ageing rather than underlying dementia

A new study by a DPUK-funded researcher has provided evidence that cognitive frailty is a feature of unhealthy yet normal ageing, rather than a sign of impending dementia.

New AI model accurately predicts the best dementia medication for each patient

A team of researchers has developed the first model for prescribing personalised medication to treat dementia. The model uses artificial intelligence (AI) to determine the most effective dementia medication for an individual based on factors such as their age, sex, and memory assessment scores.

People with both type-2 diabetes and high blood pressure have worse brain health than those with just one of these conditions

A new study co-authored by a DPUK-funded researcher has found that people with type-2 diabetes have worse overall brain health than people with high blood pressure, and that those with both conditions have even poorer brain health.

Study finds hearing aid use is linked to slower decline in thinking skills

A new study has found that hearing loss increases the risk of a precursor to dementia called mild cognitive impairment – but this increased risk is not present in people who wear hearing aids.

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