Stem Cell Network

iPSC stem cells – cells derived from human skin or blood samples – are used to investigate fundamental disease processes on a micro scale. Working at this intricate level of detail allows scientists to examine the molecular changes that underpin the development of brain diseases.

Technology resources

Automated liquid handling system used to perform a media change on a plate containing iPSC-derived neurons © Anna Lukala

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UK-wide expertise

Scientist changing media on her iPSC-derived neuronal cultures © Anna Lukala

Our networked research programmes

Cohort derived stem cells research

Cohort stem cells

Repurposing drug libraries

Scientists working in the iPSC culture suite at the University of Oxford. This technology is available to the DPUK Stem Cells Network institutions. © Anna Lukala

Drug libraries

Alzheimer's Stem cell study

Incubator for cells

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Activity across the network

Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways

Lewis D. Evans et al, (2018), Cell Reports, Volume 22, 22, 3612 - 3624

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.

Haenseler W, et al, (2017), Stem cell Reports, Stem Cell Reports, June 6:8(6), 1727 - 1742

Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages.

Haenseler W, et al, (2017), Scientific Reports, Scientific Report, 7

More publications

Featured researcher: Bryan Ng

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