Stem Cell Network
iPSC stem cells – cells derived from human skin or blood samples – are used to investigate fundamental disease processes on a micro scale. Working at this intricate level of detail allows scientists to examine the molecular changes that underpin the development of brain diseases.
Technology resources
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UK-wide expertise
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Cohort derived stem cells research
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Repurposing drug libraries
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Alzheimer's Stem cell study
Activity across the network
Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways
Lewis D. Evans et al, (2018), Cell Reports, Volume 22, 22, 3612 - 3624
A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.
Haenseler W, et al, (2017), Stem cell Reports, Stem Cell Reports, June 6:8(6), 1727 - 1742
Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages.
Haenseler W, et al, (2017), Scientific Reports, Scientific Report, 7
Featured researcher: Bryan Ng