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Sheffield joins DPUK imaging network with new PET-MR scanner

The University of Sheffield’s new PET-MR scanner is to become part of the DPUK imaging network, supporting research into the detection and treatment of dementia.

Next DPUK datathon to take place virtually in November

DPUK’s next datathon – the second to be held virtually – will take place from 16-27 November, it has been announced today.

Mental health disorders are an important predictor of cognitive decline, study shows

Anxiety and depression are more important predictors of cognitive decline than factors such as cardiovascular disease or diabetes, new analysis has shown.

Study shows value of big data in highlighting effects of childhood adversity

New research has provided further evidence of the link between childhood emotional abuse and changes in the structure of the brain, highlighting the power of big data to shed light on how our early experiences affect us in later life.

DPUK response to the government Roadmap on research and development

Comment by Professor John Gallacher, Director of Dementias Platform UK

New study suggests childhood intelligence plays protective role against late-life terminal decline

Researchers from University College London (UCL), the University of Edinburgh and the University of Montreal have shown that higher childhood intelligence has a long-term association with levels of cognitive function – even towards the end of life.

Virtual DPUK datathon kick starts dementia cohort research online

An international group of scientists from universities and industry is logging into the first virtual DPUK datathon which starts today.

Professor Kia Nobre elected to National Academy of Sciences

DPUK scientist Professor Kia Nobre has been elected to the National Academy of Sciences in recognition of her distinguished achievements in cognitive neuroscience.

Researchers assess reliability of UK Biobank cognitive tests

DPUK-funded researchers have published the results of their investigation into the reliability and validity of cognitive tests undertaken as part of the UK Biobank health data cohort.

Comment: COVID has exposed the need for flexible global data access

General

At a time when the work of disease modellers has been thrust into the spotlight, DPUK’s director, Professor John Gallacher, comments on the important role of technology platforms which democratise access to global health data.

Scientists show link between ‘toxic’ Alzheimer’s protein and impairments in brain communication networks

DPUK-funded researchers have shown for the first time a link between the accumulation of an Alzheimer’s-associated protein and the function of communication networks within the brain’s nervous system.

DPUK Data Portal: new paper outlines ambitious vision for future of cohort research

A new paper shows how the Dementias Platform UK (DPUK) Data Portal is transforming the way researchers access vital health data that could hold the key to tackling one of the world’s most pressing medical challenges.

Study demonstrates existence of 'accumulators and non-accumulators' of Alzheimer's proteins

A new study led by Dr Ivan Koychev of Dementias Platform UK has found that some people experience a rapid accumulation of two proteins in the brain associated with the onset of Alzheimer's disease: amyloid and p-Tau.

Celebrating research success in World Parkinson's Month

Stem cells

In the last few years, one of the labs in the DPUK Stem Cell network has been at the forefront of a groundbreaking approach in Parkinson’s and dementia research: human cell models of neurodegenerative disease. Their pioneering work is deepening our understanding of what goes wrong in some types of brain cells, and it is fundamental to the screening of new drugs to combat degenerative processes.

DPUK position on coronavirus

New webpage featuring information and guidance

Ulster datathon cancelled

We are monitoring the COVID19 situation and it is with regret that we have decided to postpone the Ulster datathon.

Wales leads the way in dementia research

Health records from over 80% of the Welsh population have been used to create the UK’s first national-scale health database for dementia research. DPUK researchers have used Welsh NHS records to create the new resource, allowing doctors and scientists to investigate fundamental questions about dementia with greater confidence, paving the way for new treatments.

New brain scan may pinpoint early progression of Alzheimer’s disease

DPUK enabled experimental medicine

The New therapeutics in Alzheimer's Disease (NTAD) study, supported by Dementias Platform UK (DPUK), is testing new brain scans that are revealing early changes in the brain that are a signature of Alzheimer’s disease. These markers for the disease will be used to test whether experimental treatments can delay, or even prevent, the progression of the disease.

DPUK brain imaging: harmonisation study launch

The first participant in the final stage to prepare DPUK’s scanners for multi-site dementia research comes in for their brain scan today

DPUK researchers take up international opportunities

Two early career scientists have used their DPUK funding to pursue international dementia research.

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