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This work package focused on developing and applying state-of-the-art genetic data analysis methods to DPUK cohorts to demonstrate the potential of informatics portals for conducting integrated genetic analyses. It led to the successfully development of the DPUK Genetics Portal to operate alongside the DPUK Data Portal and Imaging Portal. The team has successfully generated novel findings in the genetic risk for dementias and implicated other inflammation biomarkers in the prediction of dementia.


DPUK final report