Seizures as an early symptom of autosomal dominant Alzheimer's disease
JonathanVöglein, SoheylNoachtar, EricMcDade, Kimberly A.Quaid, Stephen Salloway, Bernardino Ghetti, James Noble, Sarah Berman, Jasmeer Chhatwal, Hiroshi Mori, Nick Fox, Ricardo Allegri, Colin L.Masters, VirginiaBuckles, John M.Ringman, MartinRossor, Peter R.Schofield, ReisaSperling, AdrianDaneka
Seizure prevalence is increased in cognitively asymptomatic ADAD mutation carriers. Epileptic seizures have a predictive value for mutation carrier status in ADAD. Seizures may manifest early in the cognitive healthy state of ADAD.