Experimental medicine 9 – Expanding DPUK genetics and integrating with inflammation/immunity research
The aim of this work was to genotype 2000 samples from individuals enrolled in DPUK cohorts and make this data available on the DPUK Data Portal. As well as enrichment of the data connected with the DPUK cohorts, the work would allow the generation of Alzheimer’s disease (AD) polygenic risk scores (PRS). This methodology has been established, and reported, as part of DPUK work package 14a.