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Highlights Tau mutations cause microtubule-mediated deformation of the nucleus in dementia Nuclear deformation results in defective nucleocytoplasmic transport Neuronal nuclei are deformed in the post-mortem frontotemporal dementia brain Disrupted nucleocytoplasmic transport is shared in multiple dementias

More information Original publication

DOI

10.1016/j.celrep.2018.12.085

Type

Journal article

Publisher

Science Direct

Publication Date

15/01/2019

Volume

26

Pages

582 - 593

Addresses

https://www.sciencedirect.com/science/article/pii/S221112471832045X?via%3Dihub

Keywords

Frontotemporal Dementia