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Aβ42/Aβ40 and Aβ42/Aβ38 Ratios Are Associated with Measures of Gait Variability and Activities of Daily Living in Mild Alzheimer’s Disease: A Pilot Study

Following from the gait protocol paper, this work shows that gait measures correlate with biochemical measures of disease processes. Specifically, CSF measures of Abeta peptide ratios correlated with step-time and step-length suggesting that early AD pathology affects the cognitive and motor control of gait.

Following from the gait protocol paper, this work shows that gait measures correlate with biochemical measures of disease processes. Specifically, CSF measures of Abeta peptide ratios correlated with step-time and step-length suggesting that early AD pathology affects the cognitive and motor control of gait.

More information Original publication

DOI

10.3233/JAD-180622

Type

Journal article

Publication Date

9/2018

Volume

65

Pages

1377 - 1383

Addresses

https://content.iospress.com/articles/journal-of-alzheimers-disease/jad180622

Keywords

Alzheimer’s disease, amyloid, biomarkers, cerebrospinal fluid proteins, gait