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Clinical Studies Register
Our Clinical Studies Register comprises more than 58,000 research participants who have already undergone extensive characterisation and have pre-existing consent for re-contact through their parent DPUK cohort.
Great Minds
Great Minds is a register of over 13,000 highly characterised research volunteers. It is a resource available for researchers enabling precision-matching for studies.
Great Minds Members Event - Decoding Dementia: Biomarkers, Big Data, and the Future of Diagnosis
This special Great Minds event brought together leading experts to explore how biomarkers, big data, and artificial intelligence are transforming dementia research and diagnosis. Our distinguished panel discussed the remarkable developments in blood-based biomarkers over the past five years, examined their clinical validity and readiness for NHS implementation, and explored the potential of AI in dementia care. The event provided valuable insights into how these innovations are shaping the future of personalised medicine and early detection in dementia.
DPUK Datathons
DPUK Datathons are FREE ONLINE EVENTS. They are a key part of our data analyst training programme, placing researchers in multidisciplinary teams to generate valuable new findings in dementia research using cohorts in the DPUK Data Portal.
TDF Register Volunteers
The DPUK Trials Delivery Framework Register serves as a national repository of valuable information, including memory scores, clinical history, brain scan results, and medications, collected from local research registers at patients' local sites. By agreeing to place their data in the Register, individuals gain the opportunity to be contacted for future research studies within the Trials Delivery Framework that align with their suitability.
IMPRINT & IMPACT
The Immune Profiling in Early Cognitive Disorders (IMPRINT) study investigates the role of neuroinflammation in the onset and progression of neurodegenerative diseases including Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). Inflammation is the process by which the immune system (white blood cells and other proteins) work to protect the body from things that may harm it. Whilst this is an important process to protect the body, in some instances the inflammation itself can be too extreme or continue for too long and then actually be harmful rather than helpful. Neuroinflammation (inflammation in the brain) has long been associated with dementia, as immune cells work to clean up proteins which build up in the brains of those affected by the condition. There now exists increasing evidence that the immune system, through
NTAD & SHINE
The Synaptic Health theme of Dementias Platform UK, aims to understand how synaptic changes lead to cognitive impairment; and how these differences can best be measured in humans and used to support early interventions in neurodegenerative diseases. Two studies have been undertaken. NTAD (which has now been completed) & SHINE (a current study which began in 2023).