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Testing potential biological signs, known as 'biomarkers', of cognitive ability in late life is of interest for both theory and practice in dementia research. This is a DPUK funded study, led by Ian Deary at the University of Edinburgh.

Hidden in the make-up of our blood might be some of the signs which could be predictive of someone developing dementia. In this experimental medicine study, the team is examining one aspect of cognitive ability, looking to see if there is any relationship with specific proteins – lipidomics and lipoproteins – which are found in the blood.

What’s the goal of the study?

Can measures related to these specific blood plasma proteins be helpful in identifying people who are at risk of Alzheimer’s disease? That’s the question that the researchers are trying to answer. Their results could provide data which could support potential therapeutic strategies for vascular causes of cognitive decline and dementia.