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The ROADMAP initiative was created to facilitate the open collaboration among a variety of stakeholders to efficiently use real world evidence (RWE) for the benefit of patients with Alzheimer’s disease and their carers. The first objective of the study is to validate a simple natural disease progression model in people with Alzheimer's disease.

It additionally supports a pilot exercise of data extraction, harmonisation, integration and analysis. Results from this exercise will be used to establish a set of procedures for repeated access to different types of data for the validation of different disease models.