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Retrospective data analysis of genotypic and selected phenotypic data from individuals with ADAD seen at the Dementia Research Centre in London. Results indicate ADAD phenotypes are heterogenous with age at onset and clinical features influenced by mutation position and causative gene. This highlights the need for genetic testing in young patients with dementia and additional neurological features, especially if there is a family history of AD or no family history available.

More information Original publication

DOI

https://doi.org/10.1016/S1474-4422(16)30193-4

Type

Journal article

Publisher

Elsevier

Publication Date

12/2016

Volume

15

Pages

1326 - 1335

Addresses

https://www.sciencedirect.com/science/article/pii/S1474442216301934?via%3Dihub