Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.
Skip to main content

Using participants from the DIAN study demonstrated that possessing one copy of the brain-derived neurotrophic factor (BDNF) Met 66 allele increased the severity of impairment in episodic memory and hippocampal function in preclinical autosomal dominant Alzheimer’s disease. The work shows that BDNF is important to the preclinical presentation of AD.

More information Original publication

DOI

https://doi.org/10.1093/brain/aww200

Publication Date

10/2016

Volume

139

Pages

2766 - 2777

Addresses

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815565/

Keywords

Alzheimer’s disease, amyloid-β, tau, dementia, genetics