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Publications

On this page, you'll find links to recently published scientific papers that have been supported by DPUK, and our research practice reports.

Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study

Christopher A Lane, et al, (2019), Lancet, 942 - 952

An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2

Natalie Connor-Robson et al, (2019), Elsevier, 127, 512 - 526

Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer’s disease

Jonathan Vöglein et al, (2019), Brain A journal of Neurology, 142, 1429 - 1440

Genetic analysis suggests high misassignment rates in clinical Alzheimer's cases and controls

V. Escott-Price et al, (2019), Neurobiology of Aging, 77, 178 - 182

Seizures as an early symptom of autosomal dominant Alzheimer's disease

JonathanVöglein et al, (2019), Neurobiology of Aging, 76, 18 - 23

Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer’s disease

Ivan Koychev et al, (2019), BMJ, 9

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease

et al, (2019), Molecular Psychairty

Associations between vascular risk factors and brain MRI indices in UK Biobank

S.R. Cox et al, (2019), European Heart Journal

Random forest prediction of Alzheimer’s disease using pairwise selection from time series data

P. J. Moore et al, (2019), Plos One, 2

Cellular α -synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons

Federico Zambon et al, (2019), Human Molecular Genetics

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

O. Preische et al, (2019), Nature Medicine, 277 - 283

Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia

Francesco Paonessa et al, (2019), Cell Reports, 26, 582 - 593

Sex-specific moderation by lifestyle and psychosocial factors on the genetic contributions to adiposity in 112,151 individuals from UK Biobank

Calvin, C et al, (2019), Nature Scientific Reports

Using a birth cohort to study brain health and preclinical dementia: recruitment and participation rates in Insight 46

Sarah-Naomi James et al, (2018), BMC

White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer’s disease

Miguel Ángel Araque Caballero et al, (2018), Brain, 1411, 3065 - 3080

Aβ42/Aβ40 and Aβ42/Aβ38 Ratios Are Associated with Measures of Gait Variability and Activities of Daily Living in Mild Alzheimer’s Disease: A Pilot Study

Koychev, Ivan et al, (2018), Journal of Alzheimer's Disease, 65, 1377 - 1383

Reduced acquisition time PET pharmacokinetic modelling using simultaneous ASL–MRI: proof of concept

Catherine J Scott et al, (2018), Sage Journals

PET Tau and Amyloid-β Burden in Mild Alzheimer's Disease: Divergent Relationship with Age, Cognition, and Cerebrospinal Fluid Biomarkers

Koychev, Ivan et al, (2018), Journal of Alzheimer's Disease, 60, 283 - 293

Data Services for Cohort Studies: Increasing the impact of existing research studies and epidemiological readiness

North, L et al, (2018), International Journal ofPopulation Data Science, 3

Pathological correlates of white matter hyperintensities in a case of progranulin mutation associated frontotemporal dementia

Ione O.C. Woollacott et al, (2018), Neurocase, 24, 166 - 174

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