Differentiation – brain cells

Each of the institutes in the Stem Cells Network have optimised protocols which successfully enable the differentiation of reprogrammed iPSCs towards various brains cells including: microglia, cortical neurons, astrocytes and dendrocytes, dopaminergic neurons, organoids, and medium spiny neurons.

Astrocytes and dendrocytes

David Storey's group at the University of Edinburgh. For more information contact karen.burr@ed.ac.uk.

Microglia

Sally Cowley’s group at the University of Oxford. For more information contact sally.cowley@path.ox.ac.uk or jane.vowles@path.ox.ac.uk.

Cortical neurons

Rick Livesy’s group at the University of Cambridge. For more information contact

james.smith@gurdon.cam.ac.uk or rick@gurdon.cam.ac.uk  

Thomas Warner's group at UCL. For more information contact t.warner@ucl.ac.uk

Dopaminergic neurons

Richard Wade-Martins' group at the University of Oxford. For more information contact: richard.wade-martins@dpag.ox.ac.uk, brent.ryan@dpag.ox.ac.uk or deepak.kumar@dpag.ox.ac.uk.

Organoids

Rick Livesy’s group at the University of Cambridge. For more information contact rick@gurdon.cam.ac.uk or james.smith@gurdon.cam.ac.uk.

Medium spiny neurons

Nick Allen’s group at Cardiff University. For more information contact CopeEL@cardiff.ac.uk.