Anxiety and depression are more important predictors of cognitive decline than factors such as cardiovascular disease or diabetes, new analysis has shown.
New research has provided further evidence of the link between childhood emotional abuse and changes in the structure of the brain, highlighting the power of big data to shed light on how our early experiences affect us in later life.
Researchers from University College London (UCL), the University of Edinburgh and the University of Montreal have shown that higher childhood intelligence has a long-term association with levels of cognitive function \u2013 even towards the end of life.
DPUK scientist Professor Kia Nobre has been elected to the National Academy of Sciences in recognition of her distinguished achievements in cognitive neuroscience.
DPUK-funded researchers have published the results of their investigation into the reliability and validity of cognitive tests undertaken as part of the UK Biobank health data cohort.
At a time when the work of disease modellers has been thrust into the spotlight, DPUK\u2019s director, Professor John Gallacher, comments on the important role of technology platforms which democratise access to global health data.
DPUK-funded researchers have shown for the first time a link between the accumulation of an Alzheimer\u2019s-associated protein and the function of communication networks within the brain\u2019s nervous system.
A new paper shows how the Dementias Platform UK (DPUK) Data Portal is transforming the way researchers access vital health data that could hold the key to tackling one of the world\u2019s most pressing medical challenges.
A new study led by Dr Ivan Koychev of Dementias Platform UK has found that some people experience a rapid accumulation of two proteins in the brain associated with the onset of Alzheimer's disease: amyloid and p-Tau.
In the last few years, one of the labs in the DPUK Stem Cell network has been at the forefront of a groundbreaking approach in Parkinson\u2019s and dementia research: human cell models of neurodegenerative disease. Their pioneering work is deepening our understanding of what goes wrong in some types of brain cells, and it is fundamental to the screening of new drugs to combat degenerative processes.
Health records from over 80% of the Welsh population have been used to create the UK\u2019s first national-scale health database for dementia research. DPUK researchers have used Welsh NHS records to create the new resource, allowing doctors and scientists to investigate fundamental questions about dementia with greater confidence, paving the way for new treatments.
The New Therapeutics in Alzheimer's Disease (NTAD) study, supported by Dementias Platform UK (DPUK), is testing new brain scans that are revealing early changes in the brain that are a signature of Alzheimer\u2019s disease.
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