University of Cambridge
Principal Investigator in DPUK’s Stem Cells Network and founding director of ARUK's Stem Cell Research Centre at the Gurdon Institute, University of Cambridge. Rick has:
- Contributed to the 150 iPSC stem cell lines – derived from human skin or blood samples – to to investigate disease and test potential treatments
- Started a programme of testing repurposed drugs as potential treatments for dementia
- Established and leads of Gen2 Neuroscience Ltd which developing drugs using the latest stem cell technology.
Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia
Francesco Paonessa et al, (2019), Cell Reports, 26, 582 - 593
Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia.
Brownjohn PW, et al, (2018), Stem Cell Reports, 10, 1294 - 1307
Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways
Lewis D. Evans et al, (2018), Cell Reports, Volume 22, 22, 3612 - 3624